Abstract: This paper aims to shed light on the use of genetic algorithm to solve for the N Queens problem on values of N that are too large to compute using the simple backtracking method. The N ...

For this tutorial (EAS BBJ traits), download and unpack the EAS archives from Zenodo, plus the HapMap3 allele list used by munge_sumstats.py (see note below). EAS genome-wide LD scores for univariate ...

Single-cell genomics (scRNA-seq, scATAC-seq, spatial transcriptomics, and multiome assays) resolves molecular variation at the level of individual cells. When integrated with GWAS, these data enable a ...

Aberrant Cas9 expression from mammalian promoters in E. coli causes guide-specific toxicity that skews CRISPR library representation in all-in-one Cas9 vectors. Replacing EF-1α with PGK reduces ...