Using mice, lab-grown cells and clues from a related disorder, researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in the ...

EXTENSIVE clinical data have been accumulated during recent years that support the view that scleroderma is a systemic disease. In addition to cutaneous involvement, which remains the cardinal ...

Scleroderma is a range of disorders in which the skin and connective tissues tighten and harden. It is a long-term, progressive disease. This means it gradually gets worse. Share on Pinterest ...

Scleroderma on the face can cause symptoms that may affect your appearance, including the texture, discoloration, and elasticity of your skin. Medications, facial exercises, and dermatological ...

A new analysis finds that compared to Caucasians, African-Americans with systemic scleroderma have more antibodies in the blood that are linked to severe complications and an increased likelihood of ...

Systemic sclerosis (SSc), or scleroderma, is a chronic, multisystem autoimmune rheumatic disease characterized by exaggerated fibrosis, vasculopathy, and derangements of the immune system. When ...

The scleroderma skin pinch test checks the thickness and elasticity of your skin. It can help doctors diagnose and monitor scleroderma, an autoimmune condition that causes inflammation and thickening ...

Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...