The ubiquitin-proteasome system (UPS) orchestrates targeted protein degradation and remodelling in mammalian sperm, underpinning functional maturation, fertilisation and post-fertilisation events. In ...

Mammalian spermatozoa require finely tuned energy metabolism to sustain motility, capacitation and ultimate fertilisation. Two primary pathways supply adenosine triphosphate (ATP): glycolysis, ...

There are many potential causes of infertility, and it can be challenging to pin down just what the problem is when a couple is having trouble getting pregnant. Now, researchers show that a few key ...