Localized scleroderma, as the term denotes, is localized to the skin on the hands and face. It is characterized by slow progression and rarely transforms to the systemic type. Localized scleroderma is ...

Localized scleroderma is a rare connective tissue disorder characterized by hardening and thickening of the skin due to increased collagen density. A quarter of patients affected also experience ...

Researchers conducted a retrospective cohort study of 114 patients (68% female; median age at onset, 8.3 years; 92% White) with juvenile localized scleroderma from the National Registry for Childhood ...

Scleroderma (meaning “hard skin” in Greek) is synonymous with morphea, although the latter term is usually reserved for a benign form of localized disease. All forms of scleroderma are ultimately ...

Systemic sclerosis (SSc), or scleroderma, is a chronic, multisystem autoimmune rheumatic disease characterized by exaggerated fibrosis, vasculopathy, and derangements of the immune system. When ...

Clinical enrollment for an open-label, single-arm Phase 1/2 trial of FCX-013 was initiated in August 2018. Fibrocell Science announced that the Food and Drug Administration (FDA) has granted Fast ...

Fibrocell Science has submitted an Investigational New Drug Application (IND) with the FDA for a gene therapy candidate to treat moderate to severe localized scleroderma. Fibrocell Science has ...

Scleroderma, also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. It also may cause problems in the blood vessels, internal organs and ...

Disclosure: Kevin Deane, MD, has disclosed the following relevant financial relationships: Receiving grant funding from: NIH for the study of genetic and environmental factors that may influence the ...

Scleroderma is a rare and often fatal disease, causing the thickening of tissue, that currently lacks a cure and any effective treatments. A group of researchers is looking to change that. The group ...