The neurotransmitter orexin regulates motivated behaviors such as arousal and feeding—and is now implicated in behaviors associated with addiction in rats. The release of orexin onto dopamine cells ...

In a recent review published in the Nutrients Journal, researchers examined the current evidence of the intricate relationship between orexin, rapid eye movement (REM) sleep, and appetite. Study: ...

推荐 为解决orexin在全身麻醉觉醒中的作用机制不明的问题，研究人员开展了orexin对伏隔核（NAc）神经元活动及与前额叶皮层通讯影响的研究。结果表明orexin通过激活D1R+神经元恢复NAc与前额叶皮层通讯促进觉醒，为麻醉觉醒机制研究提供新思路。 论文解读 在现代 ...

The orexin system, comprising the neuropeptides orexin A and B (hypocretins) and their receptors (OX1R and OX2R), is centred in the lateral hypothalamus and exerts widespread influence across the ...

The concentration of glucose in the blood of humans continuously changes in response to what they eat and the activities they engage in. While many studies have investigated changes in blood glucose, ...

本文揭示Orexin受体OX2R激动剂通过特异性神经环路改善发作性睡病（NT1）症状的突破性发现。研究通过构建orexin DTR 转基因小鼠 ...

Researchers at the University of Pennsylvania School of Medicine have discovered that the recently identified neurotransmitter orexin (also known as hypocretin) influences reward processing by ...

When the orexin neurons in the brain are stimulated, pupils expand, new research in mice shows. Orexin is central to the regulation of pupil size. When the orexin system is switched off, the pupils ...

Orexin, named after its role in feeding regulation, is a potent endogenous sleep/wake state regulator and is expected to play an essential role in controlling the cross-talk mechanism between ...

Researchers reveal orexin's crucial role in deciding between physical activity and high-reward foods. Key to tackling obesity and sedentary behavior. Orexin is essential in choosing between exercise ...

That lucky friend of yours — the one who barely gains weight when eating the same things you eat, even though your waistline expands — might have a hormone called orexin to thank. A new study shows ...