NMDA receptors are ionotropic glutamate receptors that mediate excitatory neurotransmission and underpin synaptic plasticity, learning and memory. Their unique voltage-dependent block by magnesium and ...

Researchers restored NMDA receptor function by targeting SLC6A20 in autism models. In animal studies, the treatment improved ...

A research team has identified a molecular mechanism that coordinates the operation of the N-methyl-D-aspartate (NMDA) glutamate receptor, which is key to regulating excitatory synapse function in the ...

A new study reveals that targeting the SLC6A20 glycine transporter with ASOs restores NMDAR function and reverses adult autism behaviors.

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

Neurons generated from stem cells (from skin fibroblasts) of a patient with sporadic Alzheimer’s disease. Visualized with a specific green fluorescent marker. Nuclei are shown in blue. Researchers ...

BUFFALO, N.Y. – Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders.

Adenosine receptors are key neuromodulators that regulate neuronal excitability, synaptic transmission and neuroinflammation. Two principal subtypes, A1 and A2A, exert opposing effects on cAMP ...

Viruses. Current Pharmaceutical Design, 25(43),4579-88. 7. Wang, H.* (2022). COVID-19, Anti-NMDA Receptor Encephalitis and MicroRNA. Fronters in Immunology, 13:825103.

Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated. If cancer arises from cellular mutation, why don't ...