Mitochondria lie at the heart of cellular energy production and metabolic regulation, and their impairment is increasingly recognised as a driver of cardiovascular pathology. In the arterial wall, ...

Mitochondria are pivotal to neuronal health, supplying the bulk of cellular ATP, regulating calcium homeostasis and orchestrating apoptotic signalling. In neurodegenerative diseases such as ...

Cancer is fundamentally a disease of aging. As global populations grow older, the incidence of age-associated cancers, ...

The paradigm of modern public health is shifting toward a multi-dimensional understanding of how environmental and genetic factors interact to shape human ...

Changes in how brain cells generate energy may drive the development of Alzheimer's disease and influence how patients respond to therapy, according to a new study from Mayo Clinic researchers. The ...

Presentations highlight clinical outcomes in pediatric PCQD subjects and translational evidence supporting tissue delivery and mitochondrial ...

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare. Patients ...

A new study published in Engineering has uncovered a regulatory mechanism linking lysosomal function to mitochondrial ...

Researchers discovered that declining levels of phosphatidylcholine may be a major cause of age-related mitochondrial ...

Scripps Research postdoctoral researcher Kaushik Chanda explores the mechanisms by which non-coding transcripts modulate neuronal function and structural integrity during learning and memory loss.

Proof-of-concept SHEPHERD study will assess SUL-238's effects on mitochondrial function in patients with Parkinson's ...

Stealth BioTherapeutics Holdings Inc., a commercial-stage biotechnology company focused on the discovery, development, and commercialization of novel therapies for rare and age-related diseases driven ...