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ROS响应性MgO@SiO2纳米胶囊调控氧化应激治疗骨关节炎的作用与机制
本综述系统阐述了ROS响应性MgO@SiO2纳米胶囊的构建及其在骨关节炎(OA)治疗中的应用。通过SiO2包覆实现MgO纳米颗粒(NPs)的缓释,显著延长Mg2+在关节腔的滞留时间(从12小时至3-5天),并证实低浓度(5 mM)可有效清除活性氧(ROS)、抑制炎症因子(IL-6、MMP-13 ...
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