LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

A new tool enables biomedical researchers from around the world to quickly see the connections between lipids and proteins inside cells, thanks to a new initiative led by scientists at Oregon Health & ...

Precise quantification and annotation of individual lipids is critical for understanding the complicated lipid function in biological systems. But achieving both concurrently is challenging.

Obesity and obesity-associated diseases, such as type 2 diabetes mellitus and cardiovascular diseases, have reached pandemic levels worldwide and are major threats to human life. Lipid species within ...

When we consume fats (also called lipids) in our diet, they can be metabolized or stored to provide energy for the body. But they are also involved in regulating the genes expressed within—and the ...

In a recent study published in the journal Nature Metabolism, a team of researchers conducted detailed longitudinal profiling and analysis of the lipidome using plasma samples from over a hundred ...

Hepatic lipid homeostasis is critical for both cellular function and overall metabolic health. Disruptions in lipid homeostasis can lead to fatty liver diseases, which have become a significant global ...

Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the ...

Scientists who add detergents to their cell preps, take heed: You might be consigning the most interesting stuff to the trash bin. Not proteins, surely, or nucleic acids, but lipids. A class of ...

Researchers at Tongji University have identified arachidonic acid (ARA) metabolism as a critical regulator of early human embryo implantation. Using a novel in vitro co-culture system of human ...