Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...

What is an RNA vaccine? RNA vaccines, or messenger RNA (mRNA) vaccines, are a relatively new type of vaccine that delivers mRNA molecules to human cells, instructing them to produce specific antigens.

Researchers have made a significant advance in understanding how genes are controlled in living organisms. The new study focuses on critical snippets of RNA in the tiny, transparent roundworm ...

Researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines. RNA-based medicines are one of the most promising ways to fight human disease, as ...

Oceans churned with lava. Air filled thick with smoke. Asteroids stormed down incessantly. Life during the Hadean Eon four billion years ago was a struggle, and yet that was when it began. 1,2 With no ...

A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand how RNA works. The method, published in Molecular Cell, is a powerful ...

Researchers led by Davide Incarnato at the University of Groningen have demonstrated that the FDA-approved cancer drug mitoxantrone works against RNA not simply by attaching to it, but by forcing it ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life. But the inner workings of this ...

Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the roundworm's ...

RNA is usually portrayed as a molecule that works deep inside the cell, helping to turn genetic information into proteins. But new research led by Utrecht University scientist Jack Li shows that RNA ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...

Life on Earth may have started with a molecule that still runs our cells today. As researchers probe ribonucleic acid in the lab and in ancient rocks and space dust, RNA is yielding clues that are far ...