Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...

DNA mismatch repair (MMR) is a conserved pathway that preserves genome integrity by recognising and correcting base–base mismatches and insertion–deletion loops arising during replication and ...

The preservation of genomic integrity is vital, particularly following ultraviolet irradiation, which can induce harmful DNA lesions. Photolyases are light‐activated flavoenzymes that harness blue ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair, ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for improving cancer treatment outcomes. The result was published in Cell Death & ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is ...

Researchers have uncovered how specific DNA rearrangements called inverted triplications contribute to the development of various genetic diseases. The study reveals that during DNA repair, segments ...

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 ...

Huntington's disease is a genetic disorder that kills nerve cells in the brain, causing people to lose their cognitive and motor abilities. New research led by Thomas Jefferson University researcher ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

Naked mole-rats are well known for both their wrinkly appearance and for their unexpectedly long lives. The source of this extended lifespan has been under scrutiny for decades. While many rodents are ...