To optimize the final formulation for a drug, it must meet many criteria beyond producing a safe and effective product. For example, it must be stable and amenable to various manufacturing steps, such ...

A problem for biopharmaceutical companies comes as degraded proteins lead to ineffective and possibly dangerous medicines for their clients. Drug companies work on formulation development to protect ...

Researchers at ETH Zurich have identified a compound that targets a previously overlooked protein aggregation mechanism in ...

Desire to Improve Therapeutic Proteins at Molecular Level Drives Bioformulation Advances While pharmaceutical formulations have always been part science, part art, the complexity of todays drugs has ...

Stability is one of the main quality characteristics in formulation studies of prospective therapeutic biomolecules. Researchers depend on high-throughput screening techniques to reduce the funds, ...

Layered drug nanoparticles can now be produced efficiently and at scale using a microfluidic method that eliminates purification and improves consistency. Since its adaptation to nanoscale materials, ...

Scientists have successfully tested the use of machine learning models to guide the design of long-acting injectable drug formulations. The potential for machine learning algorithms to accelerate drug ...

98% of drugs do not reach the brain, as the blood–brain barrier (BBB) separates peripheral blood circulation from the central nervous system (CNS). Galmed has developed, in collaboration with Barcode ...