In late November, a few days before he was set to line up against Myles Garrett, San Francisco 49ers' All-Pro left tackle Trent Williams said he hadn't lost any sleep over the matchup. Then he smiled.

Facing the Los Angeles Rams in Australia to open the regular season is brutal for the San Francisco 49ers. Any opponent would’ve been challenging given how taxing the travel, acclimation to the ...

The San Francisco 49ers believe they're being written off this offseason amid buzz with the Rams and Seahawks.

Sean McVay and the Los Angeles Rams’ upcoming historic matchup against the San Francisco 49ers to begin their respective 2026 regular-season slates has no shortage of storylines, and the NFL just ...